The bootloader is the first software that runs on your machine. Many hardware architectures have a very simple startup routine which reads a very simple bootloader from the beginning of the internal hard disk, then transfers control to it. Other architectures have startup routines which are able to understand more of the contents of the hard disk, and directly start a more advanced bootloader.
GRUB1 is the GNU bootloader. GRUB provides advanced functionality, and is capable of loading several different kernels (such as Mach, Linux, DOS, and the *BSD family). See Introduction.
GNU Mach conforms to the Multiboot specification which defines an interface between the bootloader and the components that run very early at startup. GNU Mach can be started by any bootloader which supports the multiboot standard. After the bootloader loaded the kernel image to a designated address in the system memory, it jumps into the startup code of the kernel. This code initializes the kernel and detects the available hardware devices. Afterwards, the first system task is started. See Overview.